The world’s most rich and resilient wild nutrients like Norwegian Reindeer Liver and Sea Buckthorn, support your skin from the inside out. We spent two years developing three targeted formulas. Backed by our 60-day guarantee.
Save up to 42% on your first order with automatic refillsCancel anytime. 29% OFF all future orders.
You're on the official Norse Organics storeShipped directly from us. Our 60-day guarantee covers orders placed here only.
SUBSCRIBE & GET 60-DAY GUARANTEE
FAST 2–7 DAYS DELIVERY
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WARNING: LOW STOCK NOTICE
Sold out 12x last year. Secure yours before they're gone. Recommended: Subscribe to never run out.
What's In The Kit?
Your skin reflects what's going on inside. This system gives your body daily support from three angles, alongside your skincare routine.
1 x Gut Repair & Liver Support Capsules (90 capsules)
Milk thistle, reindeer liver and minerals to support liver function and digestion.*
1 x Hormonal Support Drops (30 ml)
Plant extracts to support healthy hormone balance.*
1 x Wild Nordic Cod Liver Oil (150 ml)
Omega-3s and vitamins A and D to support healthy skin.*
Each kit lasts 30 days. Choose Female or Male: the capsules and drops change, the cod liver oil is the same.
Who is it for?
For adults who want to support their skin from the inside:
Women and men over 18 whose skin changes with their cycle, stress, diet or hormones.
Not for pregnant or nursing women. Contains fish (cod) and animal-based ingredients. See real customer results →
Ingredients We Use
Ancestral foods, plant extracts and minerals. Each formula is made for different needs in women and men.
Step 1: Gut Repair & Liver Support Capsules
MILK THISTLEREINDEER LIVERZINC
Milk Thistle supports healthy liver function.* Reindeer Liver is a nutrient-dense organ food, a traditional source of vitamins and minerals. Zinc supports healthy skin and immune function.* Turmeric supports a healthy inflammatory response,* and Dandelion Root supports digestion.*
Female adds: Calcium D-Glucarate and DIM to support healthy estrogen metabolism.* L-Theanine for a sense of calm.*
Female: Spearmint has traditionally been used to support hormone balance in women.* Reishi supports your body's response to stress.*
Include Sea Buckthorn, Black Seed Oil, Vitamin D3 and K2. Sweetened with monk fruit.
Step 3: Wild Nordic Cod Liver Oil
OMEGA-3VITAMIN A
598 mg of DHA and EPA per teaspoon to support healthy skin and a balanced inflammatory response.* Naturally rich in Vitamin A, which supports skin health,* and Vitamin D. Natural lemon flavor.
Full list: Cod Liver Oil 4.6 g (DHA 322 mg, EPA 276 mg), Vitamin A 1380 mcg RAE, Vitamin D 11.5 mcg, Vitamin E 0.48 mg. Other ingredients: Natural Lemon Flavor, Mixed Tocopherols.
How Do I Use It
Three steps, spread across your day.
Morning, before breakfast
Take 2 capsules on an empty stomach.
With your first meal
Take one full dropper (1 ml) of the drops mixed in a glass of water.
After your last meal
Take 1 teaspoon (5 ml) of cod liver oil.
Keep using your skincare routine. This system works from the inside.
What results can I expect?
Supplements take time, so stay consistent. Follow all three steps every day and give your body time to adjust. Results vary from person to person. See real customer results →
Clearer skin in 60 days or money back
Why 60 days? Your body needs time. Follow the system every day for the full 60 days. Not happy? You get your money back.
These are the guarantee terms you must follow to be eligible for the satisfaction guarantee. The guarantee only applies to rituals, and to subscription orders. Max 1 per customer or order, we refund a maximum of 1x ritual per order or customer. Follow usage instructions, meaning you have used the products as instructed.
Steps to claim it. First, fill out the form. Then we will get back to you around 2 weeks after submission. *These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
If you have any medical condition, allergy, are taking medication, pregnant or nursing, consult your healthcare professional before taking any dietary supplement. Keep out of reach of children.
NO WATER, FILLERS OR BS
ONLY COLD-PRESSED OILS
NO HEATING OF OILS
NO PARABENS/ PARAFFINE
100% NATURAL/ NO CHEMICALS
NON GMO
NO PESTICIDES/ HERBICIDES
NO HORMONE DISRUPTORS
- dr. Laurel Ash, naturopath
"As a specialist I appreciate Norse Organics and highly recommend these formulas for any patient on an acne healing journey.”
- dr. Laurel Ash, naturopath
Key Ingredients,Mixed to Work Together
Rentierleber
Das stärkste natürliche Multivitamin. Reich an bioverfügbarem Vitamin A, B12, Eisen und Kupfer für die normale Hautmaintenance.
Mariendistel
Traditionell verwendet, um die normale Leberfunktion zu unterstützen.
Löwenzahnwurzel
Traditionell verwendet, um einen gesunden Gallenfluss zu unterstützen.
Curcumin
29-mal besser aufnehmbar. Unterstützt eine gesunde Darmschleimhaut.
CALCIUM
Unterstützt die normale Verarbeitung von Hormonen in der Leber
Zink-Piklonat
Essentielles Mineral für normale Haut und Immunfunktion.
Magnesium
Beruhigt die Stressreaktion, unterstützt über 300 enzymatische Reaktionen.
Kupfer
Trägt zur normalen Kollagenbildung bei und aktiviert wichtige antioxidative Enzyme, um deine Hautzellen zu schützen.
SELEN
Starkes Antioxidans, das deine Haut speziell vor oxidativem Stress und Umweltgiften schützt
L-Theanin
Unterstützt eine gesunde Stressreaktion, von der auch die Haut profitiert
DIM
Unterstützt einen normalen Östrogenstoffwechsel
Calcium D-Glucarate
Unterstützt die normale Verarbeitung von Östrogen in der Leber
Spearmint Leaf Extract
Untersucht auf seine Wirkung auf den Androgenspiegel bei Frauen
Reishi-Extrakt
Der „Pilz der Unsterblichkeit“, unterstützt eine gesunde Stressreaktion
Brennnesselwurzel
Unterstützt einen gesunden Testosteronstoffwechsel und setzt gebundene Hormone frei.
Sanddorn
Mit 190 bioaktiven Stoffen nährt es deine Haut tiefgreifend, während es Reparatur, Hydratation und natürliche Ausstrahlung unterstützt.
Schwarzkümmelöl
Seit langem in der traditionellen Medizin geschätzt, reich an Thymochinon
Vitamin D3 + K2
Das Vitamin-Duo, das eine normale Haut- und Hormonfunktion unterstützt
Lebertran
Reich an EPA/DHA-Omega-3-Fettsäuren, die eine gesunde Entzündungsreaktion unterstützen.
Vitamin A (aus Lebertran)
Trägt zum Erhalt normaler Haut bei.
Vitamin D (aus Lebertran)
Unterstützt die Immunbalance und Hormonproduktion – nicht künstliches D3
Vitamin E
Ein starkes Antioxidans und natürliches Konservierungsmittel, das die Reinheit und Wirksamkeit des Öls ohne künstliche Zusatzstoffe bewahrt.
Ultimate Gut & Liver Support (Female)
Rentierleberpulver
Mariendistelextrakt (80 % Silymarin)
Kurkumawurzelextrakt
Löwenzahnwurzelextrakt 4:1
L-Theanin
Diindolylmethan (DIM)
Magnesium-Bisglycinat
Calcium-D-Glucarat 500 mg
Zink-Piklonat
BioPerine®
Kupfer-Bisglycinat
Selen (als L-Selenomethionin)
Ultimate Hormonal Support (Female)
Spearmint-Blattextrakt (10:1)
Reishi-Extrakt (10:1)
Brennnesselwurzelextrakt (10:1)
SANDDORN-Beerenextrakt (10:1)
Schwarzkümmelöl (Thymoquinon)
VITAMIN D (als Cholecalciferol)
BioPerine®
Vitamin K2
Ultimate Omega Support
Lebertran
Vitamin A (aus Lebertran)
Vitamin D (aus Lebertran)
VITAMIN E (als d-Alpha-Tocopherol)
3rd party tested
0 pesticides
0 hormone disruptors
100% natural
774.381+ Happy CustomersBefore & Afters
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Our Return Policy is simple: Results in 60 days or your money back*
Our Return Policy is simple: Results in 60 days or your money back*
Our Return Policy is simple: Results in 60 days or your money back*
Our Return Policy is simple: Results in 60 days or your money back*
Our Return Policy is simple: Results in 60 days or your money back*
Our Return Policy is simple: Results in 60 days or your money back*
Our Return Policy is simple: Results in 60 days or your money back*
Our Return Policy is simple: Results in 60 days or your money back*
Trusted by 774.381+ People Worldwide
Recommended by magazines and universities around the world
"The best thing you can do for your skin is keep things simple."
"Trust the reviews, this product works"
"Sold out 11 times over the past 7 months"
"So far, they have helped 774.381+ people with Acne"
"97% review success rate across all acne types, including cystic, hormonal, and rosacea"
"Rare Arctic plants and beeswax to effectively remove acne bacteria"
Ingredients come first
Every single ingredient in the jar is added with one purpose: To calm the look of breakouts fast and keep skin balanced long term. All ingredients are added in the most bioavailable and nutrient rich form: Unlike all other brands that add the cheapest version in too low doses.
NO water, fillers or bs
Only cold-pressed oils
NO HEATING OF OILS
no parabens/ paraffine
100% natural/ No chemicals
NON GMO
NO PESTICIDES/ HERBICIDES
NO HORMONE DISRUPTORS
Ultimate Gut & Liver Support (Frauen)-+
Rentierleber
Das stärkste natürliche Multivitamin. Reich an bioverfügbarem Vitamin A, B12, Eisen und Kupfer für die normale Hautmaintenance.
Mariendistel
Traditionell verwendet, um die normale Leberfunktion zu unterstützen.
Löwenzahnwurzel
Traditionell verwendet, um einen gesunden Gallenfluss zu unterstützen.
Curcumin
29-mal besser aufnehmbar. Unterstützt eine gesunde Darmschleimhaut.
CALCIUM
Unterstützt die normale Verarbeitung von Hormonen in der Leber
Zink-Piklonat
Essentielles Mineral für normale Haut und Immunfunktion.
Magnesium
Beruhigt die Stressreaktion, unterstützt über 300 enzymatische Reaktionen.
SELEN
Starkes Antioxidans, das deine Haut speziell vor oxidativem Stress und Umweltgiften schützt
Kupfer
Trägt zur normalen Kollagenbildung bei und aktiviert wichtige antioxidative Enzyme, um deine Hautzellen zu schützen.
L-Theanin
Unterstützt eine gesunde Stressreaktion, von der auch die Haut profitiert
DIM
Unterstützt einen normalen Östrogenstoffwechsel
Calcium D-Glucarate
Unterstützt die normale Verarbeitung von Östrogen in der Leber
Ultimate Hormonal Support (Frauen)-+
Spearmint Leaf Extract
Untersucht auf seine Wirkung auf den Androgenspiegel bei Frauen
Reishi-Extrakt
Der „Pilz der Unsterblichkeit“, unterstützt eine gesunde Stressreaktion
Brennnesselwurzel
Unterstützt einen gesunden Testosteronstoffwechsel und setzt gebundene Hormone frei.
Sanddorn
Mit 190 bioaktiven Stoffen nährt es deine Haut tiefgreifend, während es Reparatur, Hydratation und natürliche Ausstrahlung unterstützt.
Schwarzkümmelöl
Seit langem in der traditionellen Medizin geschätzt, reich an Thymochinon
Vitamin D3 + K2
Das Vitamin-Duo, das eine normale Haut- und Hormonfunktion unterstützt
Entzündungskontrolle-+
Lebertran
Reich an EPA/DHA-Omega-3-Fettsäuren, die eine gesunde Entzündungsreaktion unterstützen.
Vitamin A (aus Lebertran)
Trägt zum Erhalt normaler Haut bei.
Vitamin D (aus Lebertran)
Unterstützt die Immunbalance und Hormonproduktion – nicht künstliches D3
Vitamin E
Ein starkes Antioxidans und natürliches Konservierungsmittel, das die Reinheit und Wirksamkeit des Öls ohne künstliche Zusatzstoffe bewahrt.
“Stubborn Acne Finally Gone After Years of Pills, Derms, & Expensive Prescription Creams Failed Me”
What to Expect Over Your First Three Months
FINALLY YOU’LL BE ABLE TO FEEL CONFIDENT AGAIN ABOUT YOUR SKIN WHEN YOUR BODY GETS THE NUTRITION IT NEEDS TO RUN ITS OWN CHEMISTRY
1 WEEK
Reindeer Organs, Zinc and Vitamin D are already addressing your nutrient deficiencies and you will notice a big shift already.
Gut Calming Down
Milk Thistle and Reindeer Liver support a healthy gut lining.
Skin Feels Calmer
You’ll start to notice a shift in how your skin feels more calm.
Nutrients Flooding In
Your body will start absorbing the nutrients your skin needs.
1 MONTH
Cod Liver Oil lowers inflammation and Reindeer Organs supply the nutrients your body uses to make its own hormones. Creating the optimal platform for skin to heal.
Skin Regeneration Activated
Skin regeneration is already speeding up and the skin starts healing faster.
New Breakouts Slowing Down
As your hormones starts to balance, you’ll see breakouts become milder and less frequent.
Skin Feels Different
Your skin will feel lighter and smoother, you’ll love this feeling.
3 MONTHS
People will not recognize you. If you’ve battled acne, the change now visible in your skin will cause people to not recognize you!
What Most People Report At This Stage
This is the stage where most people tell us their skin has settled.
Natural Vitality & Glow
Your skin’s health has skyrocketed and this shows. A natural, youthful glow is now the new normal.
People Will Notice the Change
No more avoiding mirrors or canceling plans. People ask what changed. Your skin is no longer the first thing on your mind.
Our Return Policy is simple: Results in 60 days or your money back*
Our Return Policy is simple: Results in 60 days or your money back*
Our Return Policy is simple: Results in 60 days or your money back*
Our Return Policy is simple: Results in 60 days or your money back*
Our Return Policy is simple: Results in 60 days or your money back*
Our Return Policy is simple: Results in 60 days or your money back*
Our Return Policy is simple: Results in 60 days or your money back*
Our Return Policy is simple: Results in 60 days or your money back*
How Norse Organics Supports Skin From Three Angles
1. Wild Reindeer Organs
Reindeer Organs are the nutrition Nordic bodies ran on for centuries.
Reindeers cold-adapted organs equals stronger peptides. They are forced to produce unique compounds like Cryoprotective peptides and cold-shock protein.
ULTRA-HIGH in Carnitine. Moves fatty acids into the mitochondria to support cellular energy.
Roam above the arctic circle far away from civilization and are free of heavy metals, micro-plastics and toxins.
LONG -40° WINTERS
ReinDeer must survive extreme temperatures for months without food
EAT ARCTIC PLANTS
ReinDeer access superfood nutrition far from pollution
MONTHS WITHOUT SUN
In winter there is no sun in the Arctics. Imagine the resilience to go through months of darkness
NUTRITIONAL BOMBS
ReinDeer pack their organs with nutrition to survive extreme temperatures
ANCIENT TRADITION
For Vikings, ReinDeer organs were never just “meat”
Jules E. (40)Verified Buyer
I spent years feeling so insecure about my skin, thinking it was just my 'awkward phase.' I almost tried some scary prescriptions, but I’m so glad I found Norse Organics instead. It literally saved my skin and my confidence. I finally stopped hiding and feel like the best version of myself!
2. Ultra-Potent Herbs For Hormone Health
Top 5 herbs for hormonal balance in generous doses, paired with Vitamin D3 + K2.
Used for 1,000s of years by Vikings known for their glowing skin.
Thousands of PubMed studies confirms what the Vikings already knew. This is one of the core building blocks for clear skin.
In the most BIO-AVAILABLE and ULTRA-POTENT form: 10-200x Tincture extraction with Black Seed Oil for optimal absorption.
“I’ve NEVER seen something work this well before”
Johanne D. (38)Verified Buyer
After years of painful breakouts and endless derm appointments, I’ve finally found my holy grail. Nothing not even 'skin-clearing' yoga comes close to this. My skin is clear, the inflammation is gone, and I finally feel like myself again!
No Other Ancestral Viking Ritual Works Quite Like This
NORSE ORGANICS SUPPORTS SKIN IN 3 UNIQUE WAYS:
99% of solutions out there don’t work because of this and that’s why you’ll never get results and keep wasting your money forever.
1.
Strengthens the Gut/Liver Waste Flush System.
When your gut lining is weak or your liver is sluggish, hormones and toxins are not properly eliminated so more of that waste can show up in your skin.
Milk Thistle supports your liver while Reindeer Liver provides raw materials for a healthy gut lining. When your gut lining and liver are balanced, you'll see no more "trash" coming through your pores.
2.
The Ultimate Inside-Out Support System.
Norse Organics has been the most effective natural solution for acne. We've helped thousands achieve clear skin with our Arctic botanical formulas. But we knew topicals were only half the battle, so we spent two years developing three targeted systems to address each of the root causes of acne. Now, for the first time, you can support acne-prone skin from the inside AND outside, all with Norse Organics.
3.
What Most People Notice In The First Weeks
When androgens like DHT run high, they drive more oil production that trap dead skin cells inside your pores. Without correcting the hormonal signaling from the inside, no amount of face washing will stop the pores from clogging.
My skin is glowing and I haven't changed anything else. Diet's the same, same skincare, just added this system. The sea buckthorn is doing something real.
Bloating went down fast, didn't expect that. Skin took about a month but now my cycle breakouts are way milder. Not 100% gone but honestly the best it's been in years.
The product did nothing for my daughter. The supplements actually made her physically ill to the point of throwing up. And so far customer service has been unhelpful.
Week 1 my skin got a little angrier which freaked me out but I pushed through. Week 4 it flipped completely. Jawline is clear, gut feels way better, and I'm sleeping deeper. Would give 5 stars but the taste of the drops took some getting used to.
My dermatologist wanted to put me on the pill for acne. Wanted to try something natural first. So glad I did!!! Two months later my skin is clear and my hormones feel more balanced overall.
Tried spearmint tea, cutting dairy, every supplement on Amazon. This is the first thing that actually did something. Skin is calm in a way it hasn't been since before my period started messing everything up.
Most people feel reduced bloating and less skin redness within the first 24-48 hours. For longer-standing skin concerns, give it time. Most people notice the biggest change around the 30 to 45-day mark.
WHO IS THIS FOR?
This is for anyone who feels like they’ve "tried everything" (antibiotics, creams, 10-step routines) and still gets breakouts. Specifically, it’s for people with breakout-prone skin, hormonal ups and downs, and digestive discomfort. If your skin gets worse with stress or food, this is for you.
ARE THERE ANY SIDE EFFECTS?
Some people notice mild changes in the first week as their body adjusts. This usually settles within days. If anything persists or you feel unwell, stop taking it and speak to your doctor.
DOES IT NEED TO BE CYCLED?
No. Norse is whole-food nutrition. Your gut and skin face modern toxins every single day, so they need daily defense. You can take it indefinitely to maintain your results.
WILL IT HELP WITH BLOATING & PUFFINESS?
Yes. This is the #1 bonus benefit customers report. Omega-7 supports a healthy gut lining.
WILL IT INTERFERE WITH MY MEDICATIONS (ACCUTANE/ANTIBIOTICS)?
Speak to your doctor or pharmacist before combining any supplement with prescription medication.
DOES IT COME WITH A GUARANTEE?
100% Yes. We offer a 60-Day Money Back Guarantee. You can use the entire bottle. If you look in the mirror and don't see a transformation, we refund you.
IS THERE ANY WHEAT, SOY, OR NUTS?
Zero. We are strictly Gluten-Free, Soy-Free, Nut-Free, and Dairy-Free. We know that these are common acne triggers, so we keep our facility 100% clean of them.
HOW IS THIS DIFFERENT FROM "ZINC" OR "VITAMIN E" PILLS?
Most store-bought vitamins are synthetic isolates (made in a lab). Your body doesn't recognize them, so you pee them out. Norse uses Whole-Food Wild Extracts. Your body recognizes the DNA of the plant and absorbs it immediately.
WHAT IF I DON'T HAVE "CYSTIC" ACNE?
It still works. Even if you just have "annoying" whiteheads, oily skin, or redness, these often go together with how you feel internally. The ritual lowers your baseline inflammation, making your skin look tighter, brighter, and more ruggedly healthy, regardless of how bad your acne started.
If our products don't help you improve your skin within 60 days of daily use, we don't want your money. We know that our solution is extremely effective. But we also know that it's not going to work for everyone and their mother.
Androgen Modulation Through Spearmint Tea: Exploring Effects in PCOS and Non-PCOS Populations. Journal of the Academy of Nutrition and Dietetics. 2024. 150-participant randomized controlled trial, 12 weeks. https://www.jandonline.org/article/S2212-2672(24)00364-2/fulltext
Saeidi S, Ghanadian SM, Poostiyan N, Soltani R. Evaluation of the effectiveness of Berberis integerrima Bunge root extract combined with spearmint essential oil in the treatment of acne vulgaris: A randomized controlled clinical trial. J Cosmet Dermatol. 2024 Jul;23(7):2458-2466. doi: 10.1111/jocd.16291. Epub 2024 Mar 28. PMID: 38545754. https://pubmed.ncbi.nlm.nih.gov/38545754/
Dobrev H. Clinical and instrumental study of the efficacy of a new sebum control cream. J Cosmet Dermatol. 2007;6(2):113-8. doi: 10.1111/j.1473-2165.2007.00306.x. PMID: 17524128. 20 volunteers, 4 weeks. https://pubmed.ncbi.nlm.nih.gov/17524128/
Marks LS, Hess DL, Dorey FJ, Luz Macairan M, Cruz Santos PB, Tyler VE. Tissue effects of saw palmetto and finasteride: use of biopsy cores for in situ quantification of prostatic androgens. Urology. 2001;57(5):999-1005. PMID: 11337315. 40-man randomized controlled trial, 6 months. https://pubmed.ncbi.nlm.nih.gov/11337315/
Fujita R, Liu J, Shimizu K, Konishi F, Noda K, Kumamoto S, Ueda C, Tajiri H, Kaneko S, Suimi Y, Kondo R. Anti-androgenic activities of Ganoderma lucidum. Journal of Ethnopharmacology. 2005;102(1):107-112. PMID: 16076559. 75% decrease in uptake of DHT. https://pubmed.ncbi.nlm.nih.gov/16076559/
Akihisa T, Nakamura Y, Tagata M, Tokuda H, Yasukawa K, Uchiyama E, Suzuki T, Kimura Y. Anti-inflammatory and anti-tumor-promoting effects of triterpene acids and sterols from the fungus Ganoderma lucidum. Chemistry & Biodiversity. 2007;4(2):224-231. PMID: 17311233. 88.2% reduction in nitric oxide production (ganodermanontriol). https://pubmed.ncbi.nlm.nih.gov/17311233/
Obertreis B, Giller K, Teucher T, Behnke B, Schmitz H. Anti-inflammatory effect of Urtica dioica folia extract in comparison to caffeic malic acid. Arzneimittelforschung. 1996;46(1):52-56. PMID: 8821518. https://pubmed.ncbi.nlm.nih.gov/8821518/
Teucher T, Obertreis B, Ruttkowski T, Schmitz H. Cytokine secretion in whole blood of healthy subjects following oral administration of Urtica dioica L. plant extract. Arzneimittelforschung. 1996;46(9):906-910. PMID: 8967906. https://pubmed.ncbi.nlm.nih.gov/8967906/
Yang, B. et al. "Effects of Oral Supplementation and Topical Application of Supercritical CO₂ Extracted Sea Buckthorn Oil on Skin Ageing of Female Subjects." Journal of Applied Cosmetology, vol. 27, 2008, pp. 1–13.
Abdullahzadeh, M. & Shafiee, S. "To Compare the Effect of Sea Buckthorn and Silver Sulfadiazine Dressing on Period of Wound Healing in Patients with Second-Degree Burns: A Randomized Triple-Blind Clinical Trial." Wound Repair and Regeneration, vol. 29, no. 5, 2021, pp. 732–740. doi: 10.1111/wrr.12916
Boca, A.N. et al. "Sea Buckthorn Extract in the Treatment of Psoriasis." Experimental and Therapeutic Medicine, vol. 17, no. 2, 2019, pp. 1020–1023. doi: 10.3892/etm.2018.6983
Soleymani S, Farzaei MH, Zargaran A, Niknam S, Rahimi R. Promising plant-derived secondary metabolites for treatment of acne vulgaris: a mechanistic review. Arch Dermatol Res. 2020;312(1):5-23. / Soleymani S et al. Phytother Res. 2020. RCT, 60 patients, double-blind, placebo-controlled. Nigella sativa hydrogel (thymoquinone), twice daily, 60 days. 78% mean reduction in IGA score vs 3.3% placebo. https://pubmed.ncbi.nlm.nih.gov/31745627/
Faghihi G, Iranmanesh Z, Abtahi-Naeini B. Topical Nigella sativa (black seed) for hand eczema: a double-blind randomized clinical trial. J Dermatolog Treat. 2012. 19 patients, 2% black seed oil cream, twice daily, 4 weeks. DLQI: 75% improvement. HECSI: 75% improvement. Matched betamethasone steroid efficacy. https://pubmed.ncbi.nlm.nih.gov/22375794/
Ahmed Jawad H, Ibraheem YG, Taher KI, Al-Qaisi ZH. Effect of Nigella sativa oil on psoriasis: a clinical study. J Clin Exp Invest. 2014;5(2):221-226. 60 patients, mild-to-moderate plaque psoriasis, 12 weeks. 10% NS ointment + 500mg oral capsule 3×/day. 62.1% mean PASI reduction. 85% good-to-complete response. 18% relapse rate.
Ruikchuchit T, Juntongjin P. Role of vitamin D supplement adjunct to topical benzoyl peroxide in acne: a randomized double-blinded controlled study. Int J Womens Dermatol. 2024 Jul 1;10(3):e163. doi: 10.1097/JW9.0000000000000163. PMID: 38957412. 44-subject RCT, 16 weeks. https://pubmed.ncbi.nlm.nih.gov/38957412/
Lee DY, Yamasaki K, Rudsil J, Zouboulis CC, Park GT, Yang JM, Gallo RL. Sebocytes express functional cathelicidin antimicrobial peptides and can act to kill Propionibacterium acnes. J Invest Dermatol. 2008 Jul;128(7):1863-6. doi: 10.1038/sj.jid.5701235. PMID: 18200058. In vitro, human sebocytes. https://pubmed.ncbi.nlm.nih.gov/18200058/
Singh S, Khanna D, Kalra S. Association between serum levels of vitamin D and acne: A systematic review. J Cosmet Dermatol. 2021. PMID: 34319007. Observational data showing 4-fold higher prevalence of vitamin D deficiency in acne patients vs. healthy controls. https://pubmed.ncbi.nlm.nih.gov/34319007/
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